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dual-network porous collagen fiber (pcfs) scaffold  (BioMimetic Therapeutics)

 
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    BioMimetic Therapeutics dual-network porous collagen fiber (pcfs) scaffold
    Application of <t>PCFS</t> scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.
    Dual Network Porous Collagen Fiber (Pcfs) Scaffold, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dual-network porous collagen fiber (pcfs) scaffold/product/BioMimetic Therapeutics
    Average 90 stars, based on 1 article reviews
    dual-network porous collagen fiber (pcfs) scaffold - by Bioz Stars, 2026-03
    90/100 stars

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    1) Product Images from "Biomaterial-based strategies: a new era in spinal cord injury treatment"

    Article Title: Biomaterial-based strategies: a new era in spinal cord injury treatment

    Journal: Neural Regeneration Research

    doi: 10.4103/NRR.NRR-D-24-00844

    Application of PCFS scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.
    Figure Legend Snippet: Application of PCFS scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.

    Techniques Used: Functional Assay, Immunofluorescence, Staining, Binding Assay, Clinical Proteomics



    Similar Products

    dual-network porous collagen fiber (pcfs) scaffold  (BioMimetic Therapeutics)
    90
    BioMimetic Therapeutics dual-network porous collagen fiber (pcfs) scaffold
    Application of <t>PCFS</t> scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.
    Dual Network Porous Collagen Fiber (Pcfs) Scaffold, supplied by BioMimetic Therapeutics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/dual-network porous collagen fiber (pcfs) scaffold/product/BioMimetic Therapeutics
    Average 90 stars, based on 1 article reviews
    dual-network porous collagen fiber (pcfs) scaffold - by Bioz Stars, 2026-03
    90/100 stars
    		  Buy from Supplier

    Image Search Results


    Application of PCFS scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.

    Journal: Neural Regeneration Research

    Article Title: Biomaterial-based strategies: a new era in spinal cord injury treatment

    doi: 10.4103/NRR.NRR-D-24-00844

    Figure Lengend Snippet: Application of PCFS scaffolds loaded with CBD-NT-3 to boost functional neuronal growth and axonal regeneration for the treatment of SCI. (A) Schematic representation of SCI repair using PAO to create a biomimetic collagen scaffold with unique physical properties. (B, C) Immunofluorescence staining maps of Tuj-1 + and Map-2 + in the injured sites of the individual treatment groups. Scale bars: 1 mm (left) and 50 μm (right and below). (D) Quantitative analysis of the area of Tuj-1 + and Map-2 + cells at the injury site in the different treatment groups. * P < 0.05, ** P < 0.01, *** P < 0.001. Reprinted with permission from Zhao et al. (2024). Copyright 2024 Wiley‐VCH GmbH. CBD-NT-3: Collagen-binding domain-neurotrophin-3; DAPI: 4′,6-diamidino-2-phenylindole; EDC: N-ethyl-N′-(3-(dimethylamino)propyl)carbodiimide; LOCS: linear ordered collagen scaffolds; Map-2: microtubule-associated protein-2; NHS: N-hydroxysuccinimide; NSC: neural stem cell; PAO: plasma amine oxidase; PCFS: porous collagen fibers; SCI: spinal cord injury.

    Article Snippet: Zhao et al. (2024) developed a dual-network porous collagen fiber (PCFS) scaffold for neurogenesis using a combination of biomimetic plasma ammonia oxidase catalysis and conventional amide cross-linking.

    Techniques: Functional Assay, Immunofluorescence, Staining, Binding Assay, Clinical Proteomics